Magic mouthwash refers to a concoction of several drugs, typically available over the counter, that is often used to treat oral side effects like sores and mucositis caused by chemotherapy such as HD-MTX. The mouthwash is intended to be used as a rinse, not swallowed, so for younger patients it’s usually applied by caregivers using oral swabs.
A simple recipe for Magic mouthwash using ingredients available at almost any pharmacy or supermarket is equal parts Benadryl syrup and Maalox syrup.